Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30864137 | 1.00 | KRAS (0.38) | KRAS | |
| SCHEMBL31677116 | 0.94 | KRAS (0.45) | KRAS | |
| SCHEMBL27053659 | 0.93 | KRAS (0.38) | KRAS | |
| SCHEMBL27053695 | 0.93 | KRAS (0.38) | KRAS | |
| SCHEMBL30864112 | 0.92 | KRAS (0.38) | KRAS | |
| SCHEMBL30864064 | 0.91 | KRAS (0.34) | KRAS | |
| SCHEMBL29977316 | 0.90 | JAK1 (0.34) | KRAS | |
| SCHEMBL30864001 | 0.89 | KRAS (0.40) | KRAS | |
| SCHEMBL31154746 | 0.88 | KRAS (0.48) | KRAS | |
| SCHEMBL30942515 | 0.87 | KRAS (0.38) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4606803-A1 | KRAS G12D DEGRADATION AGENT, AND PREPARATION METHOD AND USE THEREFOR | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-08-27 | — | — | EP | disclosed |
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |