Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.74 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.67 |
| ▸ | AURKA | O14965 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 7/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MC4R | P32245 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655078 | 0.92 | MAPT (0.70) | MAPTAURKBAURKAMAPK1GAA | |
| SCHEMBL3782311 | 0.90 | GAA (0.67) | MAPTAURKBAURKAMAPK1GAA | |
| SCHEMBL403264 | 0.90 | AURKB (0.67) | MAPTAURKBAURKAMAPK1GAA | |
| SCHEMBL30864147 | 0.89 | AURKB (0.75) | MAPTAURKBAURKAMAPK1GAA | |
| SCHEMBL18998183 | 0.89 | AURKB (0.75) | MAPTAURKBAURKAMAPK1GAA | |
| SCHEMBL529114 | 0.89 | AURKB (0.66) | MAPTAURKBAURKAMAPK1GAA | |
| SCHEMBL402960 | 0.89 | MAPT (0.67) | MAPTAURKBAURKAMAPK1GAA | |
| SCHEMBL20390760 | 0.88 | AURKB (0.65) | MAPTAURKBAURKAMAPK1GAA | |
| SCHEMBL17439971 | 0.87 | AURKB (0.64) | MAPTAURKBAURKAMAPK1GAA | |
| SCHEMBL529278 | 0.86 | AURKB (0.63) | MAPTAURKBAURKAMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133672-A1 | DERIVATIVES OF QUINOLINE-3-CARBOXYLIC ACID AND THEIR MEDICAL USE | CLANOTECH AB (SE) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010133672-A1 | DERIVATIVES OF QUINOLINE-3-CARBOXYLIC ACID AND THEIR MEDICAL USE | CLANOTECH AB (SE) | 2010-11-25 | — | — | WO | disclosed |