Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.51 |
| ▸ | CSF1R | P07333 | 5/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220536 | 1.00 | EGFR (0.51) | EGFRCSF1RNUDT1PDE4BHDAC3 | |
| SCHEMBL30864145 | 0.87 | EGFR (0.51) | EGFRCSF1RNUDT1PDE4BMAPT | |
| SCHEMBL29220504 | 0.87 | EGFR (0.51) | EGFRCSF1RNUDT1PDE4BMAPT | |
| SCHEMBL23575535 | 0.84 | NUDT1 (0.48) | EGFRCSF1RNUDT1PDE4BMAPT | |
| SCHEMBL18998182 | 0.84 | EGFR (0.61) | EGFRCSF1RNUDT1PDE4BHDAC3 | |
| SCHEMBL30864150 | 0.84 | EGFR (0.61) | EGFRCSF1RNUDT1PDE4BHDAC3 | |
| SCHEMBL29220506 | 0.83 | CSF1R (0.56) | CSF1RNUDT1KMT2A | |
| SCHEMBL30864153 | 0.83 | CSF1R (0.56) | CSF1RNUDT1KMT2A | |
| SCHEMBL23575473 | 0.82 | NUDT1 (0.46) | EGFRCSF1RNUDT1MAPTRXFP1 | |
| SCHEMBL23575326 | 0.82 | NUDT1 (0.64) | EGFRCSF1RNUDT1MAPTERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117771374-A | Application of NUDT1 in preparing medicine for treating MYC high expression or MYC amplified tumor | 武汉大学 | 2024-03-29 | — | — | CN | disclosed |