Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 3/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20284612 | 0.83 | CYP2C9 (0.63) | CYP2C9NAMPTHRH4ALDH1A1GPR119 | |
| SCHEMBL31746669 | 0.82 | UCHL1 (0.40) | CYP2C9L3MBTL1ALDH1A1NPSR1LMNA | |
| SCHEMBL30204317 | 0.82 | TSHR (0.40) | L3MBTL1ALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL29587517 | 0.82 | POLB (0.51) | HRH4L3MBTL1ALDH1A1NPSR1LMNA | |
| SCHEMBL10140979 | 0.82 | NPSR1 (0.40) | L3MBTL1ALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL889108 | 0.82 | KMT2A (0.42) | HRH4L3MBTL1ALDH1A1NPSR1LMNA | |
| SCHEMBL13122937 | 0.82 | KMT2A (0.42) | HRH4L3MBTL1ALDH1A1NPSR1LMNA | |
| SCHEMBL13187564 | 0.82 | NPSR1 (0.40) | L3MBTL1ALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL1465557 | 0.79 | NR1H2 (0.42) | HRH4L3MBTL1ALDH1A1NPSR1LMNA | |
| SCHEMBL30864266 | 0.79 | POLB (0.48) | HRH4L3MBTL1ALDH1A1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858877-A | C-linked inhibitors of ENL/AF9 YEATS | 桥梁药品有限公司 | 2024-04-09 | — | — | CN | disclosed |