Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13514357 | 1.00 | ERN1 (0.47) | ERN1ALOX15CA12CA9CA1 | |
| SCHEMBL11378931 | 0.82 | ERN1 (0.63) | ERN1ALOX15CA12CA9CA1 | |
| SCHEMBL1006586 | 0.77 | ERN1 (0.69) | ERN1ALOX15CA12CA9CA1 | |
| SCHEMBL27809742 | 0.77 | ERN1 (0.47) | ERN1ALOX15CA12CA9CA1 | |
| SCHEMBL22487818 | 0.77 | ERN1 (0.47) | ERN1ALOX15CA12CA9CA1 | |
| SCHEMBL686136 | 0.76 | TYR (0.52) | GAAKMT2AMEN1MAPT | |
| SCHEMBL183266 | 0.76 | ALOX15 (0.42) | ERN1ALOX15KMT2AMEN1MAPT | |
| SCHEMBL29413980 | 0.76 | ALOX15 (0.42) | ERN1ALOX15KMT2AMEN1MAPT | |
| SCHEMBL29420732 | 0.76 | TYR (0.52) | GAAKMT2AMEN1MAPT | |
| SCHEMBL3752479 | 0.76 | ERN1 (0.45) | ERN1ALOX15CA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858877-A | C-linked inhibitors of ENL/AF9 YEATS | 桥梁药品有限公司 | 2024-04-09 | — | — | CN | disclosed |