SCHEMBL30864395

SCHEMBL30864395

CC(C)(C)c1cc(-c2ccccc2)cc(-c2ccc(Br)cc2)c1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.58
MAPK1 P28482 1/20 0.58
RXRB P28702 8/20 0.49
RXRA P19793 7/20 0.49
RXRG P48443 3/20 0.49
NPC1 O15118 1/20 0.43
NFKB1 P19838 1/20 0.43
RAB9A P51151 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KIF11 P52732 2/20 0.42
MCL1 Q07820 1/20 0.41
DHODH Q02127 1/20 0.41
EGFR P00533 1/20 0.40
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29709339 0.90 RXRB (0.53) ALDH1A1MAPK1RXRBRXRARXRG
SCHEMBL23909374 0.90 RXRB (0.53) ALDH1A1MAPK1RXRBRXRARXRG
SCHEMBL23909369 0.88 RXRB (0.55) ALDH1A1MAPK1RXRBRXRARXRG
SCHEMBL26149393 0.88 RXRB (0.53) ALDH1A1RXRBRXRARXRGKIF11
SCHEMBL5546207 0.88 RXRB (0.53) ALDH1A1RXRBRXRARXRGKIF11
SCHEMBL19274316 0.86 RXRB (0.46) ALDH1A1MAPK1RXRBRXRARXRG
SCHEMBL30096028 0.86 RXRB (0.57) ALDH1A1RXRBRXRARXRGKIF11
SCHEMBL27757672 0.86 RXRB (0.62) ALDH1A1RXRBRXRARXRGKIF11
SCHEMBL30864396 0.85 RXRB (0.50) ALDH1A1MAPK1RXRBRXRARXRG
SCHEMBL13813551 0.84 KIF11 (0.50) ALDH1A1MAPK1RXRBRXRARXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903182-A Light emitting device and polycyclic compound for use therein 三星显示有限公司 2024-04-19 CN disclosed