Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29538429 | 0.85 | HTR2A (0.39) | HTR2AHTR2CADRA2ANOTUMSLC6A2 | |
| SCHEMBL4017486 | 0.85 | HTR2A (0.39) | HTR2AHTR2CADRA2ANOTUMSLC6A2 | |
| SCHEMBL1383923 | 0.72 | HTR2A (0.43) | HTR2AHTR2CNOTUMSIGMAR1KMT2A | |
| SCHEMBL3203395 | 0.69 | HTR2A (0.35) | HTR2AHTR2CNOTUM | |
| SCHEMBL2764410 | 0.68 | HTR2A (0.51) | HTR2AHTR2CADRA2ANOTUMSIGMAR1 | |
| SCHEMBL14382337 | 0.67 | HTR2A (0.45) | HTR2AHTR2CNOTUMSIGMAR1KMT2A | |
| SCHEMBL1864062 | 0.64 | HTR2A (0.40) | HTR2AHTR2CNOTUMSIGMAR1KMT2A | |
| SCHEMBL29851785 | 0.64 | HTR2A (0.40) | HTR2AHTR2CNOTUMSIGMAR1KMT2A | |
| SCHEMBL8321637 | 0.64 | HTR2A (0.39) | HTR2AHTR2CNOTUMSIGMAR1ALDH1A1 | |
| SCHEMBL18911621 | 0.63 | HTR2A (0.73) | HTR2AHTR2CNOTUMSIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026102212-A1 | MACROCYCLIC MCL-1 INHIBITORS | VANDERBILT UNIVERSITY (US) | 2026-05-15 | — | — | WO | disclosed |
| WO-2025077825-A1 | METHODS AND COMPOSITIONS FOR TREATING CARDIO-PULMONARY DISORDERS | FAUNA BIO INCORPORATED (US) | 2025-04-17 | — | — | WO | disclosed |
| CN-117693506-A | Allosteric ketone inhibitors of phosphoinositide 3-kinase (PI 3K) for the treatment of disease | 佩特拉制药公司 | 2024-03-12 | — | — | CN | disclosed |