Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GMPS | P49915 | 2/20 | 0.85 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.65 |
| ▸ | FLT4 | P35916 | 2/20 | 0.65 |
| ▸ | KDR | P35968 | 3/20 | 0.62 |
| ▸ | EGFR | P00533 | 9/20 | 0.61 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.60 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.60 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.60 |
| ▸ | LTK | P29376 | 1/20 | 0.60 |
| ▸ | GRK5 | P34947 | 1/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.60 |
| ▸ | CDK8 | P49336 | 1/20 | 0.60 |
| ▸ | CDK7 | P50613 | 1/20 | 0.60 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.60 |
| ▸ | NEK4 | P51957 | 1/20 | 0.60 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.60 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.60 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22971857 | 0.92 | GMPS (1.00) | GMPSPDGFRBFLT4KDREGFR | |
| SCHEMBL31318107 | 0.92 | GMPS (1.00) | GMPSPDGFRBFLT4KDREGFR | |
| SCHEMBL19001586 | 0.86 | EGFR (0.70) | GMPSEGFRABCG2HTT | |
| SCHEMBL18996626 | 0.85 | EGFR (0.64) | GMPSPDGFRBFLT4KDREGFR | |
| SCHEMBL14286278 | 0.84 | EGFR (0.84) | GMPSPDGFRBFLT4KDREGFR | |
| SCHEMBL18349206 | 0.82 | EGFR (0.57) | GMPSKDREGFRCSF1RNPC1 | |
| SCHEMBL1837650 | 0.80 | ALDH1A1 (0.70) | GMPSNPC1LMNAHTTRAB9A | |
| SCHEMBL31390722 | 0.80 | ALDH1A1 (0.70) | GMPSNPC1LMNAHTTRAB9A | |
| SCHEMBL18334803 | 0.79 | EGFR (0.69) | GMPSPDGFRBFLT4KDREGFR | |
| SCHEMBL24249504 | 0.79 | GMPS (0.77) | GMPSPDGFRBFLT4KDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11955241-B2 | Pathogenic biomarkers and serum extracellular vesicular biomarkers associated with vascular malformation of endothelial cells, and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-04-09 | — | — | US | disclosed |