Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.34 |
| ▸ | TSHR | P16473 | 7/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 9/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30865153 | 0.92 | MGLL (0.51) | MGLLUSP2HPGDALDH1A1 | |
| SCHEMBL30865365 | 0.89 | MGLL (0.47) | MGLLCYP3A4TSHRCYP2D6LOXL2 | |
| SCHEMBL30865447 | 0.89 | MGLL (0.63) | MGLLCYP3A4TSHRCYP2D6LOXL2 | |
| SCHEMBL30865222 | 0.84 | MGLL (0.45) | MGLLCYP3A4TSHRCYP2D6USP2 | |
| SCHEMBL30865221 | 0.83 | MGLL (0.43) | MGLLCYP3A4TSHRCYP2D6USP2 | |
| SCHEMBL30865397 | 0.82 | MGLL (0.44) | MGLLCYP3A4TSHRCYP2D6USP2 | |
| SCHEMBL30865178 | 0.82 | MGLL (0.53) | MGLL | |
| SCHEMBL30865255 | 0.82 | MGLL (0.44) | MGLLCYP3A4TSHRCYP2D6USP2 | |
| SCHEMBL30865208 | 0.81 | MGLL (0.47) | MGLL | |
| SCHEMBL30865159 | 0.81 | MGLL (0.65) | MGLLCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608823-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. Hoffmann-La Roche AG (CH) | 2025-09-03 | — | — | EP | claimed |
| WO-2024088922-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-02 | — | — | WO | claimed |
| EP-4608823-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. Hoffmann-La Roche AG (CH) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024088922-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-02 | — | — | WO | disclosed |