Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30865131 | 0.86 | MGLL (0.57) | MGLL | |
| SCHEMBL30865402 | 0.86 | MGLL (0.42) | MGLLCYP2D6GRM2 | |
| SCHEMBL30865287 | 0.85 | MGLL (0.59) | MGLL | |
| SCHEMBL27246370 | 0.82 | MGLL (0.56) | MGLLCYP3A4CYP2D6IDO1 | |
| SCHEMBL30865235 | 0.80 | MGLL (0.53) | MGLLCYP3A4CYP2D6IDO1 | |
| SCHEMBL25325315 | 0.79 | MGLL (0.34) | MGLLGRM2 | |
| SCHEMBL30865310 | 0.79 | MGLL (0.51) | MGLLCYP3A4CYP2D6IDO1 | |
| SCHEMBL27148904 | 0.79 | MGLL (0.67) | MGLLCYP3A4CYP2D6IDO1 | |
| SCHEMBL30865475 | 0.79 | MGLL (0.51) | MGLLCYP3A4CYP2D6IDO1 | |
| SCHEMBL30865375 | 0.78 | MGLL (0.60) | MGLLCYP3A4CYP2D6IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608823-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. Hoffmann-La Roche AG (CH) | 2025-09-03 | — | — | EP | claimed |
| WO-2024088922-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-02 | — | — | WO | claimed |
| EP-4608823-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. Hoffmann-La Roche AG (CH) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024088922-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-02 | — | — | WO | disclosed |