Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30865278 | 0.89 | MGLL (0.46) | MGLLUSP2CYP1A2CYP3A4TSHR | |
| SCHEMBL30865318 | 0.86 | MGLL (0.43) | MGLLUSP2CYP1A2CYP3A4TSHR | |
| SCHEMBL30865340 | 0.85 | MGLL (0.50) | MGLL | |
| SCHEMBL30865329 | 0.84 | MGLL (0.44) | MGLL | |
| SCHEMBL30865123 | 0.83 | MGLL (0.47) | MGLL | |
| SCHEMBL30865391 | 0.83 | MGLL (0.43) | MGLL | |
| SCHEMBL30865343 | 0.83 | MGLL (0.59) | MGLLUSP2CYP1A2CYP3A4TSHR | |
| SCHEMBL30865208 | 0.82 | MGLL (0.47) | MGLL | |
| SCHEMBL30865441 | 0.81 | MGLL (0.45) | MGLL | |
| SCHEMBL30865334 | 0.81 | MGLL (0.41) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608823-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. Hoffmann-La Roche AG (CH) | 2025-09-03 | — | — | EP | claimed |
| WO-2024088922-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-02 | — | — | WO | claimed |
| EP-4608823-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. Hoffmann-La Roche AG (CH) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024088922-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-02 | — | — | WO | disclosed |