Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.56 |
| ▸ | USP2 | O75604 | 11/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.32 |
| ▸ | TSHR | P16473 | 7/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30865261 | 0.93 | MGLL (0.59) | MGLL | |
| SCHEMBL30865221 | 0.89 | MGLL (0.43) | MGLLUSP2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL30865236 | 0.87 | MGLL (0.42) | MGLLUSP2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL30865469 | 0.86 | MGLL (0.55) | MGLLUSP2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL30865447 | 0.84 | MGLL (0.63) | MGLLUSP2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL30013123 | 0.83 | MGLL (0.55) | MGLLUSP2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL30865471 | 0.83 | MGLL (0.57) | MGLLUSP2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL30865470 | 0.81 | MGLL (0.45) | MGLLUSP2 | |
| SCHEMBL30865120 | 0.81 | MGLL (0.58) | MGLLUSP2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL30865126 | 0.81 | MGLL (0.54) | MGLLUSP2CYP3A4CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608823-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. Hoffmann-La Roche AG (CH) | 2025-09-03 | — | — | EP | claimed |
| WO-2024088922-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-02 | — | — | WO | claimed |
| EP-4608823-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. Hoffmann-La Roche AG (CH) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024088922-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-02 | — | — | WO | disclosed |