Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30865598 | 0.97 | — | — | |
| SCHEMBL15568358 | 0.77 | MEN1 (0.33) | — | |
| Bromide SCHEMBL3523586 | 0.69 | — | — | |
| SCHEMBL4505762 | 0.67 | — | — | |
| SCHEMBL7358339 | 0.65 | — | — | |
| SCHEMBL2473112 | 0.63 | — | — | |
| SCHEMBL14969311 | 0.63 | — | — | |
| SCHEMBL665983 | 0.58 | — | — | |
| SCHEMBL4019277 | 0.58 | TP53 (0.30) | — | |
| SCHEMBL20099437 | 0.58 | TBXAS1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916232-A | Heterocyclic EGFR inhibitors for the treatment of cancer | 缆图药品公司 | 2024-04-19 | — | — | CN | disclosed |