SCHEMBL30865632

SCHEMBL30865632

CC(C)c1cnc(NCC(C)N(C)C)c2cnc(Cl)cc12

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24811604 1.00 KAT2B (0.36) KAT2B
SCHEMBL24813075 0.86 KAT2B (0.36) KAT2B
SCHEMBL30865599 0.86 KAT2B (0.36) KAT2B
SCHEMBL30164412 0.82 KAT2B (0.33) KAT2B
SCHEMBL24811594 0.82 KAT2B (0.33) KAT2B
SCHEMBL24810572 0.82 KDM4E (0.40)
SCHEMBL30164490 0.82 KDM4E (0.40)
SCHEMBL24811599 0.76
SCHEMBL24811598 0.74 KCNJ5 (0.37)
SCHEMBL30865601 0.74 KCNJ5 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117916232-A Heterocyclic EGFR inhibitors for the treatment of cancer 缆图药品公司 2024-04-19 CN disclosed