Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17654147 | 1.00 | GLS (0.80) | GLS | |
| SCHEMBL17654132 | 0.89 | GLS (1.00) | GLS | |
| SCHEMBL17654101 | 0.88 | GLS (0.82) | GLS | |
| SCHEMBL22193563 | 0.88 | GLS (0.75) | GLS | |
| SCHEMBL17654193 | 0.85 | GLS (0.80) | GLS | |
| SCHEMBL28452921 | 0.84 | GLS (0.90) | GLS | |
| SCHEMBL17654098 | 0.83 | GLS (1.00) | GLS | |
| SCHEMBL17654173 | 0.83 | GLS (1.00) | GLS | |
| SCHEMBL17664624 | 0.83 | GLS (1.00) | GLS | |
| SCHEMBL17654174 | 0.83 | GLS (1.00) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3713569-B1 | THERAPEUTIC PARTICLE COMPRISING A YAP1/WWRT1 INHIBITING AGENT AND THE GLUTAMINASE INHIBITING AGENT 2-CYCLOPROPYL-N-[5-(4-{ [5-(2-PHENYLACETAMIDO)-1,3,4-THIADIAZOL-2-YL]AMINO}PIPERIDIN-1-YL)-1,3,4-THIADIAZOL-2-YL] ACETAMIDE AND USE THEREOF FOR TREATING A PULMONARY DISEASE | UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) | 2024-03-13 | — | — | EP | disclosed |