Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.60 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 2/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30788023 | 0.94 | ERAP2 (0.63) | GHSRERAP2 | |
| SCHEMBL3384748 | 0.93 | GHSR (0.62) | GHSRUTS2RACEERAP2 | |
| SCHEMBL29578372 | 0.93 | GHSR (0.62) | GHSRUTS2RACEERAP2 | |
| SCHEMBL27702662 | 0.93 | GHSR (0.62) | GHSRUTS2RACEERAP2 | |
| SCHEMBL31211837 | 0.93 | ERAP2 (0.59) | GHSRUTS2RACEERAP2 | |
| SCHEMBL31593388 | 0.92 | GHSR (0.61) | GHSRUTS2RACEERAP2 | |
| SCHEMBL31468793 | 0.92 | GHSR (0.61) | GHSRUTS2RACEERAP2 | |
| SCHEMBL31468802 | 0.92 | GHSR (0.61) | GHSRUTS2RACEERAP2 | |
| SCHEMBL31468788 | 0.92 | GHSR (0.61) | GHSRUTS2RACE | |
| SCHEMBL31593305 | 0.92 | GHSR (0.61) | GHSRUTS2RACEERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605407-A2 | METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS | Endevica Bio, Inc. (US) | 2025-08-27 | — | — | EP | disclosed |
| WO-2024086381-A2 | METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS | ENDEVICA BIO, INC. (US) | 2024-04-25 | — | — | WO | disclosed |