Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660060 | 0.89 | CA1 (0.37) | CA1CA2CA4CA9 | |
| SCHEMBL657861 | 0.86 | CA1 (0.40) | CA1CA2CA4CA9 | |
| SCHEMBL2721926 | 0.85 | CA1 (0.45) | CA1CA2CA4CA9 | |
| SCHEMBL1011987 | 0.81 | CA1 (0.35) | CA1CA2CA4CA9 | |
| SCHEMBL182978 | 0.79 | CA1 (0.35) | CA1CA2CA4CA9 | |
| SCHEMBL1007938 | 0.78 | ALDH1A1 (0.37) | CA1CA2CA9 | |
| SCHEMBL2511955 | 0.78 | ALDH1A1 (0.37) | CA1CA2CA9 | |
| SCHEMBL3294493 | 0.78 | ALDH1A1 (0.37) | CA1CA2CA9 | |
| SCHEMBL1767625 | 0.78 | KDM4E (0.39) | CA1CA2CA4CA9 | |
| SCHEMBL83681 | 0.77 | CA1 (0.44) | CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100597-A1 | STABILIZED PROTEASE-CONTAINING SOLUTIONS | Bio-Ras Laboratories, Inc. (US) | 2012-04-26 | — | — | US | claimed |
| US-20120100597-A1 | STABILIZED PROTEASE-CONTAINING SOLUTIONS | Bio-Ras Laboratories, Inc. (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120077961-A1 | ENHANCED PURIFICATION OF ANTIBODIES AND ANTIBODY FRAGMENTS BY APATITE CHROMATOGRAPHY | BIO-RAD LABORATORIES, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-8093364-B2 | Enhanced purification of antibodies and antibody fragments by apatite chromatography | BIO-RAD LABORATORIES, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20110166332-A1 | ENHANCED ANTIBODY AGGREGATE REMOVAL WITH CAPTO ADHERE IN THE PRESENCE OF PROTEIN-EXCLUDED ZWITTERIONS | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2011-07-07 | — | — | US | disclosed |
| EP-2326658-A1 | ENHANCED PROTEIN AGGREGATE REMOVAL WITH MULTIMODAL ANION EXCHANGERS IN THE PRESENCE OF PROTEIN-EXCLUDED ZWITTERIONS | GE Healthcare Bio-Sciences AB (SE) | 2011-06-01 | — | — | EP | disclosed |
| EP-2287174-A1 | Enhanced purification of antibody fragments by apatite chromotography | Bio-Rad Laboratories, Inc. (US) | 2011-02-23 | — | — | EP | disclosed |
| EP-2275431-A2 | Enhanced fractionation of phosphorylated and nonphosphorylated biomolecules by apatite chromotography | BIO-RAD LABORATORIES, INC. (US) | 2011-01-19 | — | — | EP | disclosed |