Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2079714 | 0.69 | PPM1D (0.33) | L3MBTL1HCAR2 | |
| SCHEMBL22572683 | 0.66 | HCAR2 (0.36) | L3MBTL1HCAR2ALDH1A1MAPT | |
| SCHEMBL22572682 | 0.66 | HCAR2 (0.36) | L3MBTL1HCAR2ALDH1A1MAPT | |
| SCHEMBL1504150 | 0.66 | L3MBTL1 (0.39) | L3MBTL1HCAR2ALDH1A1MAPT | |
| SCHEMBL1503807 | 0.66 | L3MBTL1 (0.39) | L3MBTL1HCAR2ALDH1A1MAPT | |
| SCHEMBL1503810 | 0.66 | L3MBTL1 (0.39) | L3MBTL1HCAR2ALDH1A1MAPT | |
| SCHEMBL1504156 | 0.66 | L3MBTL1 (0.39) | L3MBTL1HCAR2ALDH1A1MAPT | |
| SCHEMBL5002684 | 0.65 | — | — | |
| SCHEMBL9597235 | 0.65 | TSHR (0.38) | L3MBTL1ALDH1A1 | |
| SCHEMBL17075099 | 0.65 | HCAR2 (0.47) | L3MBTL1HCAR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093785-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20050119486-A1 | Diamine derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093785-A1 | DIAMINE DERIVATIVES | C9, C1S, C1R | L3MBTL1 309/4885HCAR2 879/4885ALDH1A1 3529/4885 |
| US-20050119486-A1 | Diamine derivatives | C9, C1S, C1R | L3MBTL1 385/4885HCAR2 1086/4885ALDH1A1 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.