Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27319513 | 0.84 | IP6K1 (0.46) | IP6K1ALDH1A1HTTTSHRPABPC1 | |
| SCHEMBL30867145 | 0.84 | IP6K1 (0.46) | IP6K1ALDH1A1HTTTSHRPABPC1 | |
| SCHEMBL27319536 | 0.79 | IP6K1 (0.42) | IP6K1ALDH1A1HTTTSHRPABPC1 | |
| SCHEMBL30867147 | 0.77 | IP6K1 (0.41) | IP6K1ALDH1A1HTTTSHRPABPC1 | |
| SCHEMBL27319539 | 0.77 | IP6K1 (0.41) | IP6K1ALDH1A1HTTTSHRPABPC1 | |
| SCHEMBL27319530 | 0.77 | IP6K1 (0.42) | IP6K1ALDH1A1HTTTSHRPABPC1 | |
| SCHEMBL30867164 | 0.77 | IP6K1 (0.42) | IP6K1ALDH1A1HTTTSHRPABPC1 | |
| SCHEMBL27319526 | 0.76 | IP6K1 (0.41) | IP6K1ALDH1A1HTTTSHRPABPC1 | |
| SCHEMBL2077801 | 0.71 | CHRNB2 (0.67) | ALDH1A1HTTTSHRPABPC1ALOX15 | |
| SCHEMBL2179038 | 0.70 | HTT (0.51) | ALDH1A1HTTTSHRKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598931-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |