Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867244 | 0.97 | TSHR (0.60) | TSHRLMNAKMT2AMEN1MAPT | |
| SCHEMBL23248002 | 0.91 | ALDH1A1 (0.54) | TSHRLMNAKMT2AMEN1MAPT | |
| SCHEMBL22602035 | 0.91 | ALDH1A1 (0.54) | TSHRLMNAKMT2AMEN1MAPT | |
| SCHEMBL22361450 | 0.90 | ALDH1A1 (0.53) | TSHRLMNAKMT2AMEN1MAPT | |
| SCHEMBL12098303 | 0.86 | KMT2A (0.61) | TSHRLMNAKMT2AMEN1MAPT | |
| SCHEMBL889018 | 0.86 | ALDH1A1 (0.57) | TSHRLMNAKMT2AMEN1MAPT | |
| SCHEMBL13298120 | 0.86 | ALDH1A1 (0.57) | TSHRLMNAKMT2AMEN1MAPT | |
| SCHEMBL12098306 | 0.86 | KMT2A (0.61) | TSHRLMNAKMT2AMEN1MAPT | |
| SCHEMBL3296275 | 0.86 | ALDH1A1 (0.57) | TSHRLMNAKMT2AMEN1MAPT | |
| SCHEMBL4955786 | 0.86 | ALDH1A1 (0.60) | TSHRLMNAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993850-B | Modulators of integrated stress response pathways | 埃沃特克国际有限责任公司 | 2024-03-29 | — | — | CN | disclosed |