Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38653415 | 1.00 | CCR2 (0.31) | CCR2KCNH2 | |
| SCHEMBL30867942 | 1.00 | CCR2 (0.31) | CCR2KCNH2 | |
| SCHEMBL30867932 | 1.00 | CCR2 (0.31) | CCR2KCNH2 | |
| SCHEMBL30867694 | 0.96 | CCR2 (0.30) | CCR2KCNH2 | |
| SCHEMBL38654401 | 0.93 | CCR2 (0.33) | CCR2KCNH2 | |
| SCHEMBL38652948 | 0.93 | CCR2 (0.33) | CCR2KCNH2 | |
| SCHEMBL30867878 | 0.91 | EGFR (0.30) | — | |
| SCHEMBL30867796 | 0.91 | EGFR (0.30) | — | |
| SCHEMBL30868005 | 0.91 | SYK (0.32) | CCR2KCNH2 | |
| SCHEMBL38653071 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598917-A1 | HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | Amgen Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076674-A1 | HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | AMGEN INC. (US) | 2024-04-11 | — | — | WO | disclosed |