Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6040440 | 0.72 | — | — | |
| SCHEMBL10456696 | 0.71 | FFAR2 (0.34) | — | |
| SCHEMBL29682901 | 0.69 | PDE4A (0.32) | PDE10A | |
| SCHEMBL9797875 | 0.69 | — | — | |
| SCHEMBL30867766 | 0.69 | — | — | |
| SCHEMBL17200370 | 0.69 | — | — | |
| SCHEMBL21287272 | 0.68 | KDM4E (0.38) | PDE10A | |
| SCHEMBL7104509 | 0.67 | AGXT (0.36) | PDE10A | |
| SCHEMBL25778894 | 0.67 | OPRL1 (0.35) | — | |
| SCHEMBL27803144 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598917-A1 | HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | Amgen Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076674-A1 | HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | AMGEN INC. (US) | 2024-04-11 | — | — | WO | disclosed |