SCHEMBL30868481

SCHEMBL30868481

C[Si](C)(C)CCOCn1cnnc1S

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24306344 0.81 DGAT1 (0.38) DGAT1
SCHEMBL22408905 0.80 DGAT1 (0.34) DGAT1
SCHEMBL17275401 0.80 DGAT1 (0.34) DGAT1
SCHEMBL2147481 0.80 DGAT1 (0.40) DGAT1
SCHEMBL26914324 0.79 DGAT1 (0.34) DGAT1
SCHEMBL23669323 0.78 DGAT1 (0.33) DGAT1
SCHEMBL2148257 0.75 KLKB1 (0.35) DGAT1
SCHEMBL24320457 0.75 DGAT1 (0.34) DGAT1
SCHEMBL18675310 0.73 DGAT1 (0.31) DGAT1
SCHEMBL2148208 0.73 DGAT1 (0.34) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024028169-A1 NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2024-02-08 WO disclosed