Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25279405 | 0.86 | POLB (0.59) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL17373705 | 0.80 | MAPT (0.59) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL25200165 | 0.80 | MAPT (0.59) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL22175056 | 0.79 | SIRT6 (0.63) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL25447124 | 0.79 | SIRT6 (0.58) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL17047527 | 0.79 | MAPT (0.53) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL22171227 | 0.78 | SIRT6 (0.50) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL7986410 | 0.78 | SIRT6 (0.66) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL22466069 | 0.77 | POLB (0.57) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL17630980 | 0.77 | MAPT (0.51) | POLBMAPTALDH1A1SIRT6ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028169-A1 | NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2024-02-08 | — | — | WO | disclosed |