Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 5/20 | 0.42 |
| ▸ | BRD4 | O60885 | 10/20 | 0.34 |
| ▸ | ATRIP | Q8WXE1 | 2/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797688 | 0.90 | ATR (0.44) | ATRBRD4ATRIPTTKTLR2 | |
| SCHEMBL30869068 | 0.89 | ATR (0.46) | ATRBRD4ATRIPTTKCSNK2A2 | |
| SCHEMBL30869064 | 0.88 | ATR (0.41) | ATRBRD4ATRIPTLR2TLR1 | |
| SCHEMBL30869065 | 0.85 | ATR (0.42) | ATRBRD4ATRIPTLR2TLR1 | |
| SCHEMBL30869111 | 0.84 | ATR (0.41) | ATRBRD4ATRIPTLR2TLR1 | |
| SCHEMBL30797903 | 0.81 | ATR (0.50) | ATRBRD4ATRIPTTKCSNK2A2 | |
| SCHEMBL30869075 | 0.81 | ATR (0.40) | ATRBRD4ATRIPTLR2TLR1 | |
| SCHEMBL30797873 | 0.80 | ATR (0.41) | ATRBRD4CSNK2A2CSNK2A1DDB1 | |
| SCHEMBL27377168 | 0.80 | ATR (0.41) | ATRBRD4CSNK2A2CSNK2A1DDB1 | |
| SCHEMBL30797611 | 0.79 | ATR (0.47) | ATRATRIPTTKCSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584249-A1 | NOVEL COMPOUNDS AS CK2 INHIBITORS | Cambridge Enterprise Limited (GB) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024052702-A1 | NOVEL COMPOUNDS AS CK2 INHIBITORS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-03-14 | — | — | WO | disclosed |