Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27231778 | 0.92 | — | — | |
| SCHEMBL29783509 | 0.92 | — | — | |
| SCHEMBL27222228 | 0.92 | — | — | |
| SCHEMBL30869208 | 0.89 | — | — | |
| SCHEMBL30869190 | 0.87 | — | — | |
| SCHEMBL30083142 | 0.84 | BACE1 (0.45) | ALDH1A1MAPT | |
| SCHEMBL30258553 | 0.83 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL27231603 | 0.83 | NPC1 (0.51) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL27222163 | 0.83 | NPC1 (0.51) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL30869201 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598582-A1 | PROTEOLYSIS-TARGETING CHIMERAS AGAINST THE PAPAIN-LIKE PROTEASE OF SARS-COV-2 | Tocris Cookson Limited (GB) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024074849-A1 | PROTEOLYSIS-TARGETING CHIMERAS AGAINST THE PAPAIN-LIKE PROTEASE OF SARS-COV-2 | TOCRIS COOKSON LIMITED (GB) | 2024-04-11 | — | — | WO | disclosed |