Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.68 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.67 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.67 |
| ▸ | STAT3 | P40763 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | MIF | P14174 | 3/20 | 0.58 |
| ▸ | BCL2 | P10415 | 3/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325167 | 1.00 | CRBN (0.68) | CRBNDDB1HDAC3HDAC1HDAC2 | |
| SCHEMBL20242290 | 1.00 | CRBN (0.68) | CRBNDDB1HDAC3HDAC1HDAC2 | |
| SCHEMBL21333201 | 1.00 | CRBN (0.68) | CRBNDDB1HDAC3HDAC1HDAC2 | |
| SCHEMBL20142514 | 1.00 | CRBN (0.68) | CRBNDDB1HDAC3HDAC1HDAC2 | |
| SCHEMBL30189563 | 1.00 | CRBN (0.68) | CRBNDDB1HDAC3HDAC1HDAC2 | |
| SCHEMBL20242552 | 1.00 | CRBN (0.68) | CRBNDDB1HDAC3HDAC1HDAC2 | |
| SCHEMBL22326316 | 1.00 | CRBN (0.68) | CRBNDDB1HDAC3HDAC1HDAC2 | |
| SCHEMBL22834201 | 1.00 | CRBN (0.68) | CRBNDDB1HDAC3HDAC1HDAC2 | |
| SCHEMBL21179283 | 0.99 | CRBN (0.69) | CRBNDDB1HDAC3HDAC1HDAC2 | |
| SCHEMBL30189483 | 0.99 | CRBN (0.69) | CRBNDDB1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598582-A1 | PROTEOLYSIS-TARGETING CHIMERAS AGAINST THE PAPAIN-LIKE PROTEASE OF SARS-COV-2 | Tocris Cookson Limited (GB) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024074849-A1 | PROTEOLYSIS-TARGETING CHIMERAS AGAINST THE PAPAIN-LIKE PROTEASE OF SARS-COV-2 | TOCRIS COOKSON LIMITED (GB) | 2024-04-11 | — | — | WO | disclosed |