Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.37 |
| ▸ | ACE | P12821 | 3/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carnosine SCHEMBL1161010 | 0.99 | ITGB3 (0.41) | ITGB3ITGA2BPIN1ACECPB2 | |
| Carnosine SCHEMBL33768 | 0.99 | ITGB3 (0.41) | ITGB3ITGA2BPIN1ACECPB2 | |
| Carnosine SCHEMBL3904964 | 0.99 | ITGB3 (0.41) | ITGB3ITGA2BPIN1ACECPB2 | |
| Carnosine SCHEMBL33769 | 0.99 | ITGB3 (0.41) | ITGB3ITGA2BPIN1ACECPB2 | |
| Carnosine SCHEMBL1641133 | 0.97 | ITGB3 (0.40) | ITGB3ITGA2BPIN1ACECPB2 | |
| Carnosine SCHEMBL719519 | 0.97 | ITGB3 (0.40) | ITGB3ITGA2BPIN1ACECPB2 | |
| Carnosine SCHEMBL2684613 | 0.97 | ITGB3 (0.40) | ITGB3ITGA2BPIN1ACECPB2 | |
| Carnosine SCHEMBL11033195 | 0.97 | ITGB3 (0.40) | ITGB3ITGA2BPIN1ACECPB2 | |
| Carnosine SCHEMBL134705 | 0.97 | ITGB3 (0.40) | ITGB3ITGA2BPIN1ACECPB2 | |
| Carnosine SCHEMBL28033384 | 0.97 | ITGB3 (0.40) | ITGB3ITGA2BPIN1ACECPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093292-B2 | Conjugated fatty acid or alcohol, thiol-containing compound and bioavailable form of trivalent chromium; preventing metabolic dysregulation of adipocytes resulting from HIV-1 infection or chronic inflammation | BIONEXUS, LTD. (US) | 2012-01-10 | — | — | US | claimed |
| US-8093292-B2 | Conjugated fatty acid or alcohol, thiol-containing compound and bioavailable form of trivalent chromium; preventing metabolic dysregulation of adipocytes resulting from HIV-1 infection or chronic inflammation | BIONEXUS, LTD. (US) | 2012-01-10 | — | — | US | disclosed |
| US-8017651-B2 | Conjugated fatty acid or alcohol, thiol-containing compound and bioavailable form of trivalent chromium | BIONEXUS, LTD. (US) | 2011-09-13 | — | — | US | disclosed |
| US-20080114065-A1 | Methods for the treatment of HIV-1 related fat maldistribution, fasting hyperlipidemia and modification of adipocyte physiology | BIONEXUS, LTD. | 2008-05-15 | — | — | US | disclosed |
| US-20040106591-A1 | Compositions and methods for the treatment of HIV-associated fat maldistribution and hyperlipidemia | BIONEXUS, LTD. | 2004-06-03 | — | — | US | disclosed |