SCHEMBL30869501

SCHEMBL30869501

Brc1ccc2c(c1)Oc1cc(Br)cnc1N2CCOCCN1C[C@@H]2C[C@H]1CO2

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
KRAS P01116 3/20 0.32
PIM1 P11309 2/20 0.32
KCNH2 Q12809 1/20 0.31
MCHR1 Q99705 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869399 0.92 ESR1 (0.36) ESR1ESR2KRASKCNH2MCHR1
SCHEMBL30869588 0.92 ESR1 (0.36) ESR1ESR2KRASKCNH2MCHR1
SCHEMBL30869520 0.90 PIM1 (0.33) ESR1ESR2KRASPIM1KCNH2
SCHEMBL30869555 0.90 PIM1 (0.33) ESR1ESR2KRASPIM1KCNH2
SCHEMBL30869917 0.90 ESR1 (0.37) ESR1ESR2PIM1KCNH2MCHR1
SCHEMBL30869722 0.90 ESR1 (0.37) ESR1ESR2PIM1KCNH2MCHR1
SCHEMBL30869679 0.89 PIM1 (0.32) ESR1ESR2KRASPIM1KCNH2
SCHEMBL30869639 0.89 PIM1 (0.32) ESR1ESR2KRASPIM1KCNH2
SCHEMBL30869651 0.88 ESR1 (0.32) ESR1ESR2
SCHEMBL30869579 0.88 ESR1 (0.32) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed