SCHEMBL30869520

SCHEMBL30869520

Brc1ccc2c(c1)Oc1cc(Br)cnc1N2CCCCN1C[C@@H]2C[C@H]1CO2

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 3/20 0.33
KIF11 P52732 2/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
WNT1 P04628 2/20 0.31
GSK3B P49841 2/20 0.31
DYRK1A Q13627 2/20 0.31
KRAS P01116 2/20 0.31
KCNH2 Q12809 1/20 0.31
MCHR1 Q99705 1/20 0.31
ADK P55263 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869555 1.00 PIM1 (0.33) PIM1KIF11ESR1ESR2WNT1
SCHEMBL30869679 0.99 PIM1 (0.32) PIM1KIF11ESR1ESR2WNT1
SCHEMBL30869639 0.99 PIM1 (0.32) PIM1KIF11ESR1ESR2WNT1
SCHEMBL30869601 0.92 ESR1 (0.33) KIF11ESR1ESR2WNT1GSK3B
SCHEMBL30869401 0.92 ESR1 (0.33) KIF11ESR1ESR2WNT1GSK3B
SCHEMBL30869444 0.91 ESR1 (0.33) KIF11ESR1ESR2WNT1GSK3B
SCHEMBL30869687 0.91 ESR1 (0.33) KIF11ESR1ESR2WNT1GSK3B
SCHEMBL30869501 0.90 ESR1 (0.35) PIM1ESR1ESR2KRASKCNH2
SCHEMBL30869382 0.89 PIM1 (0.35) PIM1KIF11ESR1ESR2KCNH2
SCHEMBL30869553 0.89 PIM1 (0.35) PIM1KIF11ESR1ESR2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 PIM1 4177/4885KIF11 1236/4885ESR1 3546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.