SCHEMBL30869558

SCHEMBL30869558

CC(C)(C)OC(=O)N1CCN(CCN2c3ccc(Br)cc3Oc3cc(Br)cnc32)CC1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 4/20 0.40
BACE1 P56817 6/20 0.39
PIM1 P11309 1/20 0.39
ACKR3 P25106 1/20 0.36
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36
MAPT P10636 1/20 0.36
IDO1 P14902 1/20 0.36
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869425 0.80 FGFR1 (0.39)
SCHEMBL30869499 0.80 FGFR1 (0.39)
SCHEMBL30869634 0.80 FGFR1 (0.39)
SCHEMBL30869590 0.79 PIM1 (0.45) PIM1MAPT
SCHEMBL30869403 0.74 EGFR (0.43) PIM1
SCHEMBL30869652 0.74 EGFR (0.41) PIM1
SCHEMBL30869621 0.74 TSHR (0.50) PIM1MAPT
SCHEMBL30869759 0.73 HTT (0.35) PIM1MAPT
SCHEMBL30869389 0.72 AHR (0.34) PIM1
SCHEMBL31210120 0.71 CYP4F2 (0.50) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed