SCHEMBL30869403

SCHEMBL30869403

Brc1ccc2c(c1)Oc1cc(Br)cnc1N2CCCN1CCOCC1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EGFR P00533 9/20 0.43
PIM1 P11309 1/20 0.41
KDM1A O60341 2/20 0.39
TSHR P16473 1/20 0.39
LMNA P02545 1/20 0.39
KDM4E B2RXH2 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTR1A P08908 1/20 0.37
DRD2 P14416 1/20 0.37
HTR6 P50406 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869652 0.98 EGFR (0.41) EGFRPIM1KDM1ATSHRLMNA
SCHEMBL30869590 0.94 PIM1 (0.45) EGFRPIM1TSHRLMNA
SCHEMBL30869621 0.90 TSHR (0.50) EGFRPIM1TSHRKDM4ESMN1; SMN2
SCHEMBL30869412 0.90 ALDH1A1 (0.42) EGFRKDM1ATSHRKDM4ESMN1; SMN2
SCHEMBL30869654 0.88 ALDH1A1 (0.43) EGFRKDM1ATSHRKDM4ESMN1; SMN2
SCHEMBL30869430 0.85 ALDH1A1 (0.39) EGFRKDM1AKDM4E
SCHEMBL30869454 0.84 PIM1 (0.33) EGFRPIM1
SCHEMBL30869640 0.84 MAPK1 (0.47) TSHRSMN1; SMN2
SCHEMBL30869737 0.83 KDM1A (0.51) EGFRPIM1KDM1ATSHRLMNA
SCHEMBL30869544 0.82 AHR (0.34) PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed