SCHEMBL30869738

SCHEMBL30869738

Cc1cc2c(cc1-c1ccc3[nH]ncc3c1)Oc1cc(-c3ccc4[nH]ncc4c3)cnc1N2CCCCN1CC2COCC(C2)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 4/20 0.38
KCNH2 Q12809 1/20 0.38
MAP3K11 Q16584 1/20 0.34
TNIK Q9UKE5 1/20 0.34
TRPA1 O75762 2/20 0.34
LRRK2 Q5S007 1/20 0.34
ROCK2 O75116 4/20 0.33
ROCK1 Q13464 4/20 0.33
EGFR P00533 2/20 0.33
MAPK14 Q16539 2/20 0.33
MAP4K4 O95819 1/20 0.31
ERBB2 P04626 1/20 0.31
MAPK9 P45984 1/20 0.31
CSNK1D P48730 1/20 0.31
PRKD2 Q9BZL6 1/20 0.31
SLK Q9H2G2 1/20 0.31
CDC7 O00311 1/20 0.31
DAPK3 O43293 1/20 0.31
DYRK3 O43781 1/20 0.31
CDK1 P06493 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869708 0.99 CHRNA7 (0.38) CHRNA7KCNH2MAP3K11TNIKTRPA1
SCHEMBL30869505 0.98 CHRNA7 (0.38) CHRNA7KCNH2MAP3K11TNIKTRPA1
SCHEMBL30869388 0.94 CHRNA7 (0.37) CHRNA7KCNH2MAP3K11TNIKTRPA1
SCHEMBL30869560 0.91 CHRNA7 (0.41) CHRNA7KCNH2MAP3K11TNIKLRRK2
SCHEMBL30869655 0.90 CHRNA7 (0.40) CHRNA7KCNH2MAP3K11TNIKLRRK2
SCHEMBL30869598 0.90 CHRNA7 (0.41) CHRNA7KCNH2MAP3K11TNIKLRRK2
SCHEMBL30869750 0.89 CHRNA7 (0.41) CHRNA7KCNH2MAP3K11TNIKLRRK2
SCHEMBL30869563 0.89 CHRNA7 (0.35) CHRNA7KCNH2MAP3K11TNIKTRPA1
SCHEMBL30869880 0.89 CHRNA7 (0.41) CHRNA7KCNH2MAP3K11TNIKLRRK2
SCHEMBL30869773 0.87 EGFR (0.45) CHRNA7KCNH2MAP3K11TNIKTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed