Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.32 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30869498 | 0.91 | PRMT5 (0.38) | CHRNA7PRMT5WDR77KCNH2LRRK2 | |
| SCHEMBL30869535 | 0.90 | PRMT5 (0.40) | CHRNA7PRMT5WDR77KCNH2LRRK2 | |
| SCHEMBL30869738 | 0.89 | CHRNA7 (0.38) | CHRNA7KCNH2MAPK14LRRK2TRPA1 | |
| SCHEMBL30869505 | 0.89 | CHRNA7 (0.38) | CHRNA7KCNH2MAPK14LRRK2TRPA1 | |
| SCHEMBL30869708 | 0.89 | CHRNA7 (0.38) | CHRNA7KCNH2MAPK14LRRK2TRPA1 | |
| SCHEMBL30869388 | 0.87 | CHRNA7 (0.37) | CHRNA7KCNH2MAPK14LRRK2TRPA1 | |
| SCHEMBL30869750 | 0.80 | CHRNA7 (0.41) | CHRNA7PRMT5WDR77KCNH2LRRK2 | |
| SCHEMBL30869560 | 0.80 | CHRNA7 (0.41) | CHRNA7PRMT5WDR77KCNH2LRRK2 | |
| SCHEMBL30869655 | 0.79 | CHRNA7 (0.40) | CHRNA7PRMT5WDR77KCNH2LRRK2 | |
| SCHEMBL30869598 | 0.78 | CHRNA7 (0.41) | CHRNA7KCNH2LRRK2ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583868-A2 | DYNAMIN ACTIVATORS | Walden Biosciences, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054661-A2 | DYNAMIN ACTIVATORS | WALDEN BIOSCIENCES (US) | 2024-03-14 | — | — | WO | disclosed |