SCHEMBL30869841

SCHEMBL30869841

c1cc2c(cc1-c1cnc3[nH]ncc3c1)Oc1cc(-c3cnc4[nH]ncc4c3)ccc1N2CCN1CC2(COC2)C1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.37
CD38 P28907 1/20 0.37
TNIK Q9UKE5 3/20 0.36
GRIA1 P42261 1/20 0.35
PIK3C3 Q8NEB9 3/20 0.34
PIK3CA P42336 2/20 0.34
AKT1 P31749 1/20 0.34
SYK P43405 4/20 0.34
ABL1 P00519 2/20 0.33
CHEK1 O14757 2/20 0.33
PLK4 O00444 1/20 0.33
PDPK1 O15530 1/20 0.33
DYRK3 O43781 1/20 0.33
JAK2 O60674 1/20 0.33
ROCK2 O75116 1/20 0.33
PRKD3 O94806 1/20 0.33
MAP4K4 O95819 1/20 0.33
NTRK1 P04629 1/20 0.33
INSR P06213 1/20 0.33
FYN P06241 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869445 0.88 GRIA1 (0.43) CD38GRIA1AKT1SYKABL1
SCHEMBL30869745 0.86 PDE10A (0.45) PDE10ATNIKPIK3C3PIK3CAAKT1
SCHEMBL30869426 0.82 GRIA1 (0.42) CD38GRIA1AKT1SYKABL1
SCHEMBL30869796 0.82 GRIA1 (0.42) GRIA1AKT1SYKABL1CHEK1
SCHEMBL30869723 0.82 PRKCQ (0.42) CD38TNIKPIK3CAJAK2ROCK2
SCHEMBL30869822 0.82 GRIA1 (0.41) GRIA1AKT1SYKABL1CHEK1
SCHEMBL30869455 0.81 GRIA1 (0.40) TNIKGRIA1AKT1CHEK1DYRK3
SCHEMBL30869676 0.81 GRIA1 (0.40) TNIKGRIA1AKT1CHEK1DYRK3
SCHEMBL30869809 0.80 GRIA1 (0.39) TNIKGRIA1AKT1CHEK1DYRK3
SCHEMBL30869547 0.79 GRIA1 (0.38) CD38TNIKGRIA1AKT1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed