Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27379058 | 1.00 | HPGD (0.45) | HPGDRECQLEPHX1DPP4GPR119 | |
| SCHEMBL30750554 | 1.00 | HPGD (0.45) | HPGDRECQLEPHX1DPP4GPR119 | |
| SCHEMBL30750758 | 0.93 | HPGD (0.44) | HPGDRECQLEPHX1DPP4GPR119 | |
| SCHEMBL30750656 | 0.93 | HPGD (0.44) | HPGDRECQLEPHX1DPP4GPR119 | |
| SCHEMBL30750642 | 0.92 | GPR119 (0.43) | HPGDRECQLEPHX1DPP4GPR119 | |
| SCHEMBL30750727 | 0.92 | HPGD (0.43) | HPGDRECQLEPHX1DPP4GPR119 | |
| SCHEMBL21997805 | 0.92 | HPGD (0.49) | HPGDRECQLEPHX1DPP4GPR119 | |
| SCHEMBL30750720 | 0.88 | HPGD (0.44) | HPGDRECQLEPHX1DPP4GPR119 | |
| SCHEMBL21458709 | 0.88 | HPGD (0.46) | HPGDRECQLEPHX1GPR119PRMT5 | |
| SCHEMBL21458682 | 0.88 | HPGD (0.46) | HPGDRECQLEPHX1GPR119PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584275-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | Halda Therapeutics Opco, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054604-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |