Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 5/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.37 |
| ▸ | PARP1 | P09874 | 4/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.37 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27437373 | 1.00 | TNKS (0.37) | TNKSTNKS2PARP1PARP3WNT3A | |
| SCHEMBL30870725 | 0.86 | PARP1 (0.37) | TNKSTNKS2PARP1PARP3WNT3A | |
| SCHEMBL27437464 | 0.74 | TNKS (0.42) | TNKSTNKS2PARP1PARP3WNT3A | |
| SCHEMBL27436072 | 0.74 | TNKS (0.42) | TNKSTNKS2PARP1PARP3WNT3A | |
| SCHEMBL27437262 | 0.71 | PARP1 (0.55) | TNKSTNKS2PARP1PARP3WNT3A | |
| SCHEMBL27436689 | 0.71 | PARP1 (0.55) | TNKSTNKS2PARP1PARP3WNT3A | |
| SCHEMBL27436612 | 0.70 | TNKS2 (0.67) | TNKSTNKS2PARP1PARP3WNT3A | |
| SCHEMBL27437229 | 0.69 | PARP1 (0.58) | TNKSTNKS2PARP1PARP3WNT3A | |
| SCHEMBL30870708 | 0.66 | PARP1 (0.45) | TNKSTNKS2PARP1PARP3WNT3A | |
| SCHEMBL27443951 | 0.66 | PARP1 (0.45) | TNKSTNKS2PARP1PARP3WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024086246-A2 | 2-SUBSTITUTED 3,4 A, 5, 7, 8, 8 A-HEXAHYDRO-4H-THIOP YRANO [4,3- DJPYRIMIDIN-4-ONES FOR WOUND TREATMENT | Eluciderm Inc. (US) | 2024-04-25 | — | — | WO | disclosed |