SCHEMBL3087080

SCHEMBL3087080

Cc1c(F)cc(-c2nccc(Oc3cccc(C(F)(F)F)c3)n2)c(F)c1F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.47
F10 P00742 1/20 0.45
MAPT P10636 2/20 0.44
L3MBTL1 Q9Y468 3/20 0.41
ALDH1A1 P00352 2/20 0.41
POLB P06746 1/20 0.41
RAB9A P51151 1/20 0.40
PPP1CA P62136 1/20 0.39
KMT2A Q03164 1/20 0.39
KDR P35968 2/20 0.39
BRAF P15056 1/20 0.39
MAPK14 Q16539 1/20 0.39
TNNI3K Q59H18 1/20 0.39
KDM4E B2RXH2 2/20 0.38
GAA P10253 2/20 0.38
MAPK1 P28482 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7022943 0.80 GAA (0.32) FFAR4L3MBTL1GAAMAPK1
SCHEMBL5838876 0.78 CYP1A2 (0.48) FFAR4MAPTL3MBTL1ALDH1A1POLB
SCHEMBL6177990 0.77 FFAR4 (0.53) FFAR4MAPTL3MBTL1ALDH1A1POLB
SCHEMBL336755 0.77 FFAR4 (0.52) FFAR4MAPTL3MBTL1ALDH1A1POLB
SCHEMBL29387718 0.77 FFAR4 (0.52) FFAR4MAPTL3MBTL1ALDH1A1POLB
SCHEMBL6180609 0.74 FFAR4 (0.50) FFAR4MAPTL3MBTL1ALDH1A1POLB
SCHEMBL8723629 0.73 MAPT (0.52) FFAR4MAPTL3MBTL1ALDH1A1POLB
SCHEMBL8668427 0.72 GAA (0.51) FFAR4MAPTL3MBTL1ALDH1A1POLB
SCHEMBL8773158 0.71 MAPT (0.65) F10MAPTL3MBTL1ALDH1A1POLB
SCHEMBL29607042 0.71 MAPT (0.65) F10MAPTL3MBTL1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11959086-B2 Dual transit peptides for targeting polypeptides BASF Agro B.V. (NL) 2024-04-16 US disclosed
US-20190169626-A1 DUAL TRANSIT PEPTIDES FOR TARGETING POLYPEPTIDES BASF SE (DE) 2019-06-06 US disclosed
US-20100227761-A1 Agrochemical Formulations Based on Molecularly Imprinted Acrylates BASF SE (DE) 2010-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100227761-A1 Agrochemical Formulations Based on Molecularly Imprinted Acrylates AS3MT, DDT, ACR FFAR4 2752/4885F10 4368/4885MAPT 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.