Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19429612 | 0.73 | PARP1 (0.62) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL912962 | 0.73 | PARP1 (0.62) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29999040 | 0.73 | PARP1 (0.62) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4320359 | 0.69 | TTR (0.42) | GUSBKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL1137855 | 0.67 | GRM5 (0.48) | PARP1ALDH1A1 | |
| SCHEMBL29999019 | 0.66 | BRD4 (0.55) | PARP1KDM4EALDH1A1MAOAMAOB | |
| SCHEMBL22766689 | 0.66 | KDM4E (0.38) | KDM4EALDH1A1HPGD | |
| SCHEMBL339368 | 0.62 | ALOX5 (0.60) | KDM4ELMNA | |
| SCHEMBL31174603 | 0.62 | ALOX5 (0.60) | KDM4ELMNA | |
| SCHEMBL3637630 | 0.61 | PARP1 (0.56) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794534-A | Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof | 尤尼根公司 | 2024-03-29 | — | — | CN | disclosed |