Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 20/20 | 0.44 |
| ▸ | CBL | P22681 | 18/20 | 0.44 |
| ▸ | CBLC | Q9ULV8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25180087 | 0.91 | CBLB (0.47) | CBLBCBLCBLC | |
| SCHEMBL30521126 | 0.85 | CBLB (0.45) | CBLBCBLCBLC | |
| SCHEMBL31274763 | 0.85 | CBLB (0.44) | CBLBCBLCBLC | |
| SCHEMBL30872127 | 0.84 | CBLB (0.43) | CBLBCBLCBLC | |
| SCHEMBL31274123 | 0.82 | CBLB (0.54) | CBLBCBLCBLC | |
| SCHEMBL25413018 | 0.82 | CBLB (0.48) | CBLBCBLCBLC | |
| SCHEMBL25413016 | 0.82 | CBLB (0.48) | CBLBCBLCBLC | |
| SCHEMBL31251303 | 0.81 | HSD11B1 (0.31) | CBLBCBL | |
| SCHEMBL30999126 | 0.81 | CBLB (0.43) | CBLBCBLCBLC | |
| SCHEMBL22849886 | 0.81 | CBLB (0.57) | CBLBCBLCBLC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024245264-A1 | CBL-B INHIBITOR AND USE THEREOF | 海南先声再明医药股份有限公司 | 2024-12-05 | — | — | WO | disclosed |
| CN-117940404-A | Tricyclic compounds as Cbl-b inhibitors | 海南先声再明医药股份有限公司 | 2024-04-26 | — | — | CN | disclosed |