SCHEMBL30872191

SCHEMBL30872191

Oc1n[nH]c2cc(Cl)ncc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
GABRA2 P47869 1/20 0.36
GABRB2 P47870 1/20 0.36
GABRA4 P48169 1/20 0.36
GABRE P78334 1/20 0.36
GABRA6 Q16445 1/20 0.36
GABRG1 Q8N1C3 1/20 0.36
GABRG3 Q99928 1/20 0.36
GABRQ Q9UN88 1/20 0.36
KCNQ3 O43525 1/20 0.34
KCNQ2 O43526 1/20 0.34
TRPA1 O75762 1/20 0.34
KCNQ1 P51787 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14895511 0.80 GABRP (0.38) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL12466691 0.78 JAK2 (0.44) MAPK1PDPK1
SCHEMBL30056844 0.77 GABRP (0.36) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29562773 0.77 GABRP (0.36) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL21055463 0.77 GABRP (0.36) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL16580770 0.77 ADORA2A (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29562995 0.77 ADORA2A (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL14895721 0.77 GABRP (0.36) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL31144202 0.77 MAPK1 (0.34) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL27028576 0.77 MAPK1 (0.34) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978777-A Modified 6-chloro-1H-pyrazolo [4,3-C ] pyridine-alcohol-containing material and preparation method thereof 苏州求索生物科技有限公司 2025-05-13 CN claimed
CN-119978777-A Modified 6-chloro-1H-pyrazolo [4,3-C ] pyridine-alcohol-containing material and preparation method thereof 苏州求索生物科技有限公司 2025-05-13 CN disclosed
CN-117982915-A Drying, decompressing and concentrating equipment 苏州求索生物科技有限公司 2024-05-07 CN disclosed
CN-117960090-A PH value adjusting device 苏州求索生物科技有限公司 2024-05-03 CN disclosed