SCHEMBL30872201

SCHEMBL30872201

Fc1ccccc1Oc1ccccc1-c1noc(CBr)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
LMNA P02545 4/20 0.44
MAPT P10636 3/20 0.44
SMN1; SMN2 Q16637 5/20 0.42
L3MBTL1 Q9Y468 4/20 0.42
HTT P42858 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPK1 P28482 2/20 0.42
ALOX15 P16050 2/20 0.42
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
NPC1 O15118 5/20 0.41
RAB9A P51151 4/20 0.40
GAA P10253 3/20 0.40
TP53 P04637 3/20 0.40
TSHR P16473 2/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28579413 1.00 ALDH1A1 (0.44) ALDH1A1LMNAMAPTSMN1; SMN2L3MBTL1
SCHEMBL28869666 0.85 NPC1 (0.50) ALDH1A1LMNAMAPTSMN1; SMN2L3MBTL1
SCHEMBL30098391 0.81 SMN1; SMN2 (0.60) ALDH1A1MAPTSMN1; SMN2L3MBTL1HTT
SCHEMBL6042179 0.81 SMN1; SMN2 (0.60) ALDH1A1MAPTSMN1; SMN2L3MBTL1HTT
SCHEMBL202163 0.79 S1PR1 (0.51) ALDH1A1LMNAMAPTSMN1; SMN2L3MBTL1
SCHEMBL28574299 0.76 MAPT (0.41) ALDH1A1LMNAMAPTSMN1; SMN2L3MBTL1
SCHEMBL30098423 0.74 MAPT (0.50) ALDH1A1MAPTSMN1; SMN2L3MBTL1MAPK1
SCHEMBL9321473 0.74 MAPT (0.50) ALDH1A1MAPTSMN1; SMN2L3MBTL1MAPK1
SCHEMBL28869611 0.74 S1PR1 (0.53) ALDH1A1SMN1; SMN2HTTALOX15NPC1
SCHEMBL6041725 0.73 ATM (0.58) ALDH1A1MAPTSMN1; SMN2L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979628-B Diphenyl ether substituted oxime derivative and its application in agriculture 东莞市东阳光农药研发有限公司 2024-04-26 CN disclosed