Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458868 | 0.82 | OPRD1 (0.38) | OPRD1SLC6A9CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30642715 | 0.82 | OPRD1 (0.38) | OPRD1SLC6A9CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5450723 | 0.82 | OPRD1 (0.38) | OPRD1SLC6A9CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5458873 | 0.82 | OPRD1 (0.38) | OPRD1SLC6A9CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30733235 | 0.77 | OPRD1 (0.42) | OPRD1SLC6A9KDM4ECYP1A2CYP3A4 | |
| SCHEMBL2769798 | 0.76 | OPRD1 (0.42) | OPRD1SIGMAR1 | |
| SCHEMBL14671934 | 0.76 | OPRD1 (0.42) | OPRD1SIGMAR1 | |
| SCHEMBL14663826 | 0.76 | OPRD1 (0.42) | OPRD1SIGMAR1 | |
| SCHEMBL14663829 | 0.76 | OPRD1 (0.42) | OPRD1SIGMAR1 | |
| SCHEMBL14663828 | 0.76 | OPRD1 (0.42) | OPRD1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881670-A | Methods of making EGFR inhibitors | 缆图药品公司 | 2024-04-12 | — | — | CN | disclosed |