Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.42 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23352227 | 0.80 | KDM4E (0.40) | NOTUMMAPK1KDM4EALDH1A1HDAC4 | |
| SCHEMBL20168114 | 0.80 | CHRNA7 (0.52) | KDM4EALDH1A1CHRNA7LMNAHTT | |
| SCHEMBL4341894 | 0.79 | NOTUM (0.78) | NOTUMMAPK1KDM4EALDH1A1HDAC4 | |
| SCHEMBL20504631 | 0.79 | NOTUM (0.56) | NOTUMMAPK1KDM4EALDH1A1HDAC4 | |
| SCHEMBL12969407 | 0.79 | NOTUM (0.45) | NOTUMMAPK1KDM4EALDH1A1HDAC4 | |
| SCHEMBL6206765 | 0.79 | NOTUM (0.45) | NOTUMMAPK1KDM4EALDH1A1HDAC4 | |
| SCHEMBL28862451 | 0.76 | NOTUM (0.53) | NOTUMMAPK1KDM4EALDH1A1HDAC4 | |
| SCHEMBL22817092 | 0.76 | NOTUM (0.49) | NOTUMMAPK1KDM4EALDH1A1HDAC4 | |
| SCHEMBL7425143 | 0.75 | NOTUM (0.51) | NOTUMMAPK1KDM4EALDH1A1HDAC4 | |
| SCHEMBL24877382 | 0.75 | NOTUM (0.51) | NOTUMMAPK1KDM4EALDH1A1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715904-A | CDK2 degrading agents and uses thereof | 凯麦拉医疗公司 | 2024-03-15 | — | — | CN | disclosed |