Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TOP1 | P11387 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 4/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL521943 | 0.86 | ALDH1A1 (0.62) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL13942801 | 0.79 | DPP4 (0.65) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL14703073 | 0.79 | DPP4 (0.65) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL15957843 | 0.79 | DPP4 (0.65) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| Alpha-Terthienyl SCHEMBL147274 | 0.79 | DPP4 (0.65) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL23611278 | 0.79 | DPP4 (0.65) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL1105086 | 0.79 | DPP4 (0.65) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL2742433 | 0.79 | DPP4 (0.65) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL13707354 | 0.79 | DPP4 (0.65) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL499333 | 0.79 | DPP4 (0.65) | ALDH1A1KDM4ENPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1691586-B1 | CHARGE-TRANSPORTING ORGANIC MATERIAL CONTAINING COMPOUND HAVING 1,4-DITHIIN RING | NISSAN CHEMICAL IND LTD (JP) | 2015-10-14 | — | — | EP | disclosed |
| US-7795452-B2 | Charge-transporting organic material containing compound having 1,4-dithiin ring | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20070043222-A1 | Charge-transporting organic material containing compound having 1,4-dithiin ring | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1691586-A1 | CHARGE-TRANSPORTING ORGANIC MATERIAL CONTAINING COMPOUND HAVING 1,4-DITHIIN RING | Nissan Chemical Industries, Ltd. (JP) | 2006-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043222-A1 | Charge-transporting organic material containing compound having 1,4-dithiin ring | SLCO2A1, SLCO4C1, VIL1 | ALDH1A1 849/4885KDM4E 2236/4885NPC1 1070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.