Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.37 |
| ▸ | CDC25B | P30305 | 8/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101786 | 0.80 | PDE2A (0.48) | PDE2AHTR1ACA1CA2CA9 | |
| SCHEMBL16701323 | 0.80 | PDE2A (0.48) | PDE2AHTR1ACA1CA2CA9 | |
| SCHEMBL18787314 | 0.79 | PDE2A (0.51) | PDE2AHTR1ACA1CA2CA9 | |
| SCHEMBL24487830 | 0.73 | PDE2A (0.48) | PDE2AHTR1ACA1CA2CA9 | |
| SCHEMBL15254037 | 0.72 | PDE2A (0.46) | PDE2AHTR1ACA1CA2CA9 | |
| SCHEMBL18787315 | 0.72 | PDE2A (0.52) | PDE2AHTR1ACA1CA2CA9 | |
| SCHEMBL19227796 | 0.71 | PDE2A (0.49) | PDE2AHTR1ACA1CA2CA9 | |
| SCHEMBL18636426 | 0.71 | PDE2A (0.49) | PDE2AHTR1ACA1CA2CA9 | |
| SCHEMBL19644579 | 0.71 | PDE2A (0.51) | PDE2AHTR1ACA1CA2CA9 | |
| SCHEMBL24557986 | 0.71 | PDE2A (0.59) | PDE2AHTR1ACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085243-B | Pyrrolo [1,2-f ] [1,2,4] triazines useful for the treatment of respiratory syncytial virus infection | 吉利德科学公司 | 2024-04-26 | — | — | CN | disclosed |