Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | CD99 | P14209 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18380007 | 1.00 | HIF1A (0.41) | HIF1ALMNANT5EKDM4EADORA2A | |
| SCHEMBL807421 | 1.00 | HIF1A (0.41) | HIF1ALMNANT5EKDM4EADORA2A | |
| SCHEMBL16708590 | 0.90 | PNP (0.33) | HIF1ALMNANT5E | |
| SCHEMBL20943584 | 0.90 | PNP (0.33) | HIF1ALMNANT5E | |
| SCHEMBL18379740 | 0.90 | PNP (0.33) | HIF1ALMNANT5E | |
| SCHEMBL15257398 | 0.83 | HIF1A (0.43) | HIF1ALMNANT5EADORA2AADORA3 | |
| SCHEMBL16479516 | 0.81 | POLRMT (0.40) | HIF1AADORA2AADORA3ADORA1PDE2A | |
| SCHEMBL806951 | 0.81 | POLRMT (0.40) | HIF1AADORA2AADORA3ADORA1PDE2A | |
| SCHEMBL19101901 | 0.81 | POLRMT (0.40) | HIF1AADORA2AADORA3ADORA1PDE2A | |
| SCHEMBL4765542 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085243-B | Pyrrolo [1,2-f ] [1,2,4] triazines useful for the treatment of respiratory syncytial virus infection | 吉利德科学公司 | 2024-04-26 | — | — | CN | disclosed |