Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 5/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095189 | 0.86 | GPR84 (0.40) | RPS6KA2RPS6KA3L3MBTL1RXRARXRB | |
| SCHEMBL3079143 | 0.85 | GPR84 (0.42) | CSNK2A2CSNK2A1RPS6KA2RPS6KA3 | |
| SCHEMBL3087467 | 0.82 | RPS6KA3 (0.39) | HTR2AHTR2CRPS6KA2RPS6KA3MAPKAPK2 | |
| SCHEMBL3092044 | 0.80 | RPS6KA2 (0.43) | HTR2AHTR2CRPS6KA2RPS6KA3MAPKAPK2 | |
| SCHEMBL3083810 | 0.73 | RPS6KA3 (0.41) | RPS6KA2RPS6KA3MAPKAPK2 | |
| SCHEMBL3086678 | 0.73 | RPS6KA3 (0.43) | RPS6KA2RPS6KA3MAPKAPK2 | |
| SCHEMBL3084506 | 0.73 | KDM4E (0.44) | HTR2AHTR2CRPS6KA2RPS6KA3L3MBTL1 | |
| SCHEMBL3092096 | 0.73 | RPS6KA2 (0.45) | HTR2AHTR2CRPS6KA2RPS6KA3 | |
| SCHEMBL3087336 | 0.72 | RPS6KA2 (0.42) | RPS6KA2RPS6KA3MAPKAPK2 | |
| SCHEMBL3088133 | 0.71 | RPS6KA3 (0.54) | HTR2AHTR2CRPS6KA2RPS6KA3MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795247-B2 | Tetracyclic indole derivatives as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2010-09-14 | — | — | US | disclosed |
| US-20060100262-A1 | Tetracyclic indole derivatives as antiviral agents | ISTITUTO DI RICHERCHEDI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IRMB) (IT) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100262-A1 | Tetracyclic indole derivatives as antiviral agents | IDO1, ZC3HAV1, IDO2 | CSNK2A2 193/4885CSNK2B 319/4885CSNK2A1 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.