Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.61 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | PTPRB | P23467 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | PTEN | P60484 | 1/20 | 0.47 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187828 | 0.89 | SLC7A5 (0.56) | SLC7A5CYP4F2CYP4A11PPARGNR1H2 | |
| SCHEMBL30873952 | 0.85 | FFAR1 (0.55) | SLC7A5FFAR1FFAR4NR1H2NR1H3 | |
| SCHEMBL7505386 | 0.85 | CYP4F2 (0.69) | SLC7A5CYP4F2CYP4A11LOXL2 | |
| SCHEMBL31487557 | 0.85 | CYP4F2 (0.69) | SLC7A5CYP4F2CYP4A11LOXL2 | |
| SCHEMBL1000232 | 0.85 | SLC7A5 (0.64) | SLC7A5CYP4F2CYP4A11LOXL2NR1H2 | |
| SCHEMBL5382573 | 0.85 | SLC7A5 (0.60) | SLC7A5CYP4F2CYP4A11PPARGALDH1A1 | |
| SCHEMBL7504785 | 0.84 | SLC7A5 (0.63) | SLC7A5CYP4F2CYP4A11LOXL2 | |
| SCHEMBL31487728 | 0.84 | SLC7A5 (0.59) | SLC7A5CYP4F2CYP4A11ALDH1A1HPGD | |
| Adipic Acid SCHEMBL27893785 | 0.83 | SLC7A5 (0.55) | SLC7A5ALDH1A1NR1H2NR1H3MAPT | |
| SCHEMBL6160155 | 0.83 | CYP4F2 (0.71) | SLC7A5CYP4F2CYP4A11KEAP1PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013287-A | Macrocyclic immunomodulators | 百时美施贵宝公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-118613490-A | Macrocyclic immunomodulators | 百时美施贵宝公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-118076623-A | Macrocyclic immunomodulators | 百时美施贵宝公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117940445-A | Macrocyclic immunomodulators | 百时美施贵宝公司 | 2024-04-26 | — | — | CN | disclosed |