Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21409218 | 1.00 | TLR9 (0.51) | TLR9TLR8TLR7KMT2ANR3C1 | |
| SCHEMBL31255253 | 0.88 | NR3C1 (0.48) | KMT2ANR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL24735334 | 0.88 | KMT2A (0.48) | KMT2ANR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL29841519 | 0.88 | KMT2A (0.48) | KMT2ANR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL25270082 | 0.87 | NR3C1 (0.47) | TLR9TLR8TLR7KMT2ANR3C1 | |
| SCHEMBL30158156 | 0.87 | NR3C1 (0.47) | TLR9TLR8TLR7KMT2ANR3C1 | |
| SCHEMBL29841476 | 0.87 | KMT2A (0.48) | KMT2ANR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL24735190 | 0.87 | KMT2A (0.48) | KMT2ANR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL30501253 | 0.86 | NR3C1 (0.49) | KMT2ANR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL25249325 | 0.86 | NR3C1 (0.46) | TLR9TLR8TLR7KMT2ANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118754858-A | N- (3- (7H-pyrrolo [2,3-d ] pyrimidin-4-yl) phenyl) benzamide derivatives | 诺华股份有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-111936498-B | N- (3- (7H-pyrrolo [2,3-d ] pyrimidin-4-yl) phenyl) benzamide derivatives | 诺华股份有限公司 | 2024-04-16 | — | — | CN | disclosed |